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Mapping suitability for Buruli ulcer at fine spatial scales across Africa: A modelling study.


ABSTRACT: Buruli ulcer (BU) is a disabling and stigmatising neglected tropical disease (NTD). Its distribution and burden are unknown because of underdiagnosis and underreporting. It is caused by Mycobacterium ulcerans, an environmental pathogen whose environmental niche and transmission routes are not fully understood. The main control strategy is active surveillance to promote early treatment and thus limit morbidity, but these activities are mostly restricted to well-known endemic areas. A better understanding of environmental suitability for the bacterium and disease could inform targeted surveillance, and advance understanding of the ecology and burden of BU. We used previously compiled point-level datasets of BU and M. ulcerans occurrence, evidence for BU occurrence within national and sub-nat

SUBMITTER: Simpson H 

PROVIDER: S-EPMC7959670 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature