Cerebral Perfusion Pressure is Maintained in Acute Intracerebral Hemorrhage: A CT Perfusion Study.

ABSTRACT:

Background and purpose

Although blood pressure reduction has been postulated to result in a fall in cerebral perfusion pressure in patients with intracerebral hemorrhage, the latter is rarely measured. We assessed regional cerebral perfusion pressure in patients with intracerebral hemorrhage by using CT perfusion source data.

Materials and methods

Patients with acute primary intracerebral hemorrhage were randomized to target systolic blood pressures of <150 mm Hg (n = 37) or <180 mm Hg (n = 36). Regional maps of cerebral blood flow, cerebral perfusion pressure, and cerebrovascular resistance were generated by using CT perfusion source data, obtained 2 hours after randomization.

Results

Perihematoma cerebral blood flow (38.7 ± 11.9 mL/100 g/min) was reduced relative to

SUBMITTER: Tamm AS 

PROVIDER: S-EPMC7959964 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature