Regeneration of the flatworm Prosthiostomum siphunculus (Polycladida, Platyhelminthes).

ABSTRACT: Fueled by the discovery of head regeneration in triclads (planarians) two and a half centuries ago, flatworms have been the focus of regeneration research. But not all flatworms can regenerate equally well and to obtain a better picture of the characteristics and evolution of regeneration in flatworms other than planarians, the regeneration capacity and stem cell dynamics during regeneration in the flatworm order Polycladida are studied. Here, we show that as long as the brain remained at least partially intact, the polyclad Prosthiostomum siphunculus was able to regenerate submarginal eyes, cerebral eyes, pharynx, intestine and sucker. In the complete absence of the brain only wound closure was observed but no regeneration of missing organs. Amputated parts of the brain could not be regen

SUBMITTER: Schadt T 

PROVIDER: S-EPMC7960593 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature