Prenatal exposure to persistent organic pollutants and markers of obesity and cardiometabolic risk in Spanish adolescents.

ABSTRACT:

Background

Prenatal exposure to persistent organic pollutants (POPs) has been linked to cardiometabolic (CM) risk factors in childhood, but there are no studies evaluating the persistence of these associations into adolescence, a period of relevant changes in endocrine-dependent organ systems and rapid increases in lean and fat mass. We examined the associations of prenatal POP exposures with body mass index (BMI) from age 4 to 18 years, and with other CM risk markers in adolescence.

Methods

We analysed 379 children from the Spanish INMA-Menorca birth cohort study with measured cord blood POP concentrations. We calculated BMI z-scores at ages 4, 6, 11, 14 and 18 years using the WHO growth reference. Body fat % was measured at 11 and 18 years and waist-to-height ratio (WHtR)

SUBMITTER: Guil-Oumrait N 

PROVIDER: S-EPMC7960637 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature