The oralome and its dysbiosis: New insights into oral microbiome-host interactions.

ABSTRACT: The oralome is the summary of the dynamic interactions orchestrated between the ecological community of oral microorganisms (comprised of up to approximately 1000 species of bacteria, fungi, viruses, archaea and protozoa - the oral microbiome) that live in the oral cavity and the host. These microorganisms form a complex ecosystem that thrive in the dynamic oral environment in a symbiotic relationship with the human host. However, the microbial composition is significantly affected by interspecies and host-microbial interactions, which in turn, can impact the health and disease status of the host. In this review, we discuss the composition of the oralome and inter-species and host-microbial interactions that take place in the oral cavity and examine how these interactions change from healt

SUBMITTER: Radaic A 

PROVIDER: S-EPMC7960681 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature