A missense mutation in the coding region of the toll-like receptor 4 gene affects milk traits in Barki sheep.

ABSTRACT:

Objective

Milk production is one of the most desirable traits in livestock. Recently, the toll-like receptor (TLR) has been identified as a candidate gene for milk traits in cows. So far, there is no information concerning the contribution of this gene in milk traits in sheep. This study was designed to investigate the TLR 4 gene polymorphisms in Barki ewes in Egypt and then correlate that with milk traits in order to identify potential single nucleotide polymorphisms (SNPs) for these traits in sheep.

Methods

A part of the ovine TLR 4 gene was amplified in Barki ewes, to identify the SNPs. Consequently; Barki ewes were genotyped using polymerase chain reaction-single strand conformation polymorphism protocol. These genotypes were correlated with milk traits, which were the d

SUBMITTER: Sallam AM 

PROVIDER: S-EPMC7961266 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature