Molecular Genetics of Follicular-Derived Thyroid Cancer.

ABSTRACT: Thyroid cancer is the most common type of endocrine-related malignancy, whose incidence rates have increased dramatically in the last few decades. Neoplasms of follicular origin generally have excellent prognosis, with the exception of less differentiated tumors. Follicular-derived thyroid cancer can manifest as a variety of morphologically distinct entities, characterized by various degrees of differentiation and invasiveness. Histological evaluation is thus crucial for the definition of patients' prognosis. However, within each histological subtype, tumor behavior can be highly variable, and, in this respect, molecular characterization can provide insightful information to refine the risk stratification of tumors. In addition to the importance of its prognostic role, molecular testing ca

SUBMITTER: Macerola E 

PROVIDER: S-EPMC7961716 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature