Chromosome-length genome assembly and structural variations of the primal Basenji dog (Canis lupus familiaris) genome.

ABSTRACT:

Background

Basenjis are considered an ancient dog breed of central African origins that still live and hunt with tribesmen in the African Congo. Nicknamed the barkless dog, Basenjis possess unique phylogeny, geographical origins and traits, making their genome structure of great interest. The increasing number of available canid reference genomes allows us to examine the impact the choice of reference genome makes with regard to reference genome quality and breed relatedness.

Results

Here, we report two high quality de novo Basenji genome assemblies: a female, China (CanFam_Bas), and a male, Wags. We conduct pairwise comparisons and report structural variations between assembled genomes of three dog breeds: Basenji (CanFam_Bas), Boxer (CanFam3.1) and German Shepherd Dog (GSD

SUBMITTER: Edwards RJ 

PROVIDER: S-EPMC7962210 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature