Reliability of a dried urine test for comprehensive assessment of urine hormones and metabolites.

ABSTRACT:

Background

Mass spectrometry allows for analysis of multiple hormone and organic acid metabolites from small urine volumes; however, to assess the full extent of daily hormone production, 24-h urine collections are usually required. The aims of this study were, first, to confirm that mass spectrometric analysis of an array of hormones and organic acids would yield similar results in both liquid and dried urine, and, second, to determine if collection of four dried spot urine samples could be substituted for a 24-h collection when measuring reproductive hormones.

Methods

Two study populations were included in this prospective observational study. Twenty individuals collected both a spot liquid urine and dried urine on filter paper to analyze eight organic acids. A second grou

SUBMITTER: Newman M 

PROVIDER: S-EPMC7962249 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature