A Prognostic Nomogram of Colon Cancer With Liver Metastasis: A Study of the US SEER Database and a Chinese Cohort.

ABSTRACT:

Background

Among colon cancer patients, liver metastasis is a commonly deadly phenomenon, but there are few prognostic models for these patients.

Methods

The clinicopathologic data of colon cancer with liver metastasis (CCLM) patients were downloaded from the Surveillance, Epidemiology and End Results (SEER) database. All patients were randomly divided into training and internal validation sets based on the ratio of 7:3. A prognostic nomogram was established with Cox analysis in the training set, which was validated by two independent validation sets.

Results

A total of 5,700 CCLM patients were included. Age, race, tumor size, tumor site, histological type, grade, AJCC N status, carcinoembryonic antigen (CEA), lung metastasis, bone metastasis, surgery, and chemotherap

SUBMITTER: Liu C 

PROVIDER: S-EPMC7962604 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature