Stroke risk in arthritis: A systematic review and meta-analysis of cohort studies.

ABSTRACT:

Background and objective

Stroke is a major contributor to the global burden of disease. Although numerous modifiable risk factors (RF) for stroke have been identified, some remain unexplained. Increasing studies have investigated stroke risk in arthritis, but their results are inconsistent. We aimed to synthesize, quantify, and compare the risk of stroke for the major types of arthritis in cohort studies by using a systematic review and meta-analysis approach.

Methods

We searched Chinese and English databases to identify relevant studies from inception to April 30, 2020. Only studies adjusting at least for age and sex were included. We calculated pooled effect estimates for relative risk (RR) and 95% confidence interval (CI) and identified potential sources of heterogeneity

SUBMITTER: Liu W 

PROVIDER: S-EPMC7963101 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature