White Matter Injury and General Movements in High-Risk Preterm Infants.

ABSTRACT:

Background and purpose

Very preterm infants (birth weight, <1500 g) are at increased risk of cognitive and motor impairment, including cerebral palsy. These adverse neurodevelopmental outcomes are associated with white matter abnormalities on MR imaging at term-equivalent age. Cerebral palsy has been predicted by analysis of spontaneous movements in the infant termed "General Movement Assessment." The goal of this study was to determine the utility of General Movement Assessment in predicting adverse cognitive, language, and motor outcomes in very preterm infants and to identify brain imaging markers associated with both adverse outcomes and aberrant general movements.

Materials and methods

In this prospective study of 47 preterm infants of 24-30 weeks' gestation, brain MR i

SUBMITTER: Peyton C 

PROVIDER: S-EPMC7963672 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature