Quantitative Synthetic MRI in Children: Normative Intracranial Tissue Segmentation Values during Development.

ABSTRACT:

Background and purpose

Synthetic MR imaging is a new technique to create absolute R1 relaxivity (1/T1), R2 relaxivity (1/T2), and proton-density maps using a single multiple-spin-echo saturation recovery sequence. These relaxivity maps allow rapid automated intracranial segmentation of tissue types. To assess its utility in children, we created a normative data base of intracranial volume and brain parenchymal, GM, WM, CSF, and myelin volumes in a pediatric population with normal brain MRI findings using synthetic MR imaging.

Materials and methods

All multiple-spin-echo saturation recovery sequences containing brain MR imaging examinations performed during 34 months were retrospectively reviewed. Abnormal examination findings were excluded following a detailed radiographic a

SUBMITTER: McAllister A 

PROVIDER: S-EPMC7963732 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature