DTI Analysis of Presbycusis Using Voxel-Based Analysis.

ABSTRACT:

Background and purpose

Presbycusis is the most common sensory deficit in the aging population. A recent study reported using a DTI-based tractography technique to identify a lack of integrity in a portion of the auditory pathway in patients with presbycusis. The aim of our study was to investigate the white matter pathology of patients with presbycusis by using a voxel-based analysis that is highly sensitive to local intensity changes in DTI data.

Materials and methods

Fifteen patients with presbycusis and 14 age- and sex-matched healthy controls were scanned on a 3T scanner. Fractional anisotropy, mean diffusivity, axial diffusivity, and radial diffusivity were obtained from the DTI data. Intergroup statistics were implemented on these measurements, which were transformed t

SUBMITTER: Ma W 

PROVIDER: S-EPMC7963761 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature