Rest versus exercise hemodynamics for middle cerebral artery aneurysms: a computational study.

ABSTRACT:

Background and purpose

Exercise is an accepted method of improving cardiovascular health; however, the impact of increases in blood flow and heart rate on a cerebral aneurysms is unknown. This study was performed to simulate the changes in hemodynamic conditions within an intracranial aneurysm when a patient exercises.

Materials and methods

Rotational 3D digital subtraction angiograms were used to reconstruct patient-specific geometries of 3 aneurysms located at the bifurcation of the middle cerebral artery. CFD was used to solve for transient flow fields during simulated rest and exercise conditions. Inlet conditions were set by using published transcranial Doppler sonography data for the middle cerebral artery. Velocity fields were analyzed and postprocessed to provide phy

SUBMITTER: Bowker TJ 

PROVIDER: S-EPMC7964156 | biostudies-literature | 2010 Feb

REPOSITORIES: biostudies-literature