Injury to the Cerebellum in Term Asphyxiated Newborns Treated with Hypothermia.

ABSTRACT:

Background and purpose

Until now, most studies of brain injury related to term neonatal encephalopathy have focused on the cerebrum and ignored the cerebellum. We sought to evaluate whether cerebellar injury occurs in term asphyxiated neonates.

Materials and methods

Asphyxiated neonates treated with hypothermia were enrolled prospectively. Severity of brain injury in the cerebrum was scored on each MR imaging obtained during the first month of life; cerebellar injury was recorded when mentioned in the imaging or autopsy report. In addition, for some of the neonates, the ADC and fractional anisotropy were measured in 4 regions of interest in the cerebellum.

Results

One hundred seventy-two asphyxiated neonates met the criteria for hypothermia. Cerebellar injury was visi

SUBMITTER: Kwan S 

PROVIDER: S-EPMC7964687 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature