Improving Multiple Sclerosis Plaque Detection Using a Semiautomated Assistive Approach.

ABSTRACT:

Background and purpose

Treating MS with disease-modifying drugs relies on accurate MR imaging follow-up to determine the treatment effect. We aimed to develop and validate a semiautomated software platform to facilitate detection of new lesions and improved lesions.

Materials and methods

We developed VisTarsier to assist manual comparison of volumetric FLAIR sequences by using interstudy registration, resectioning, and color-map overlays that highlight new lesions and improved lesions. Using the software, 2 neuroradiologists retrospectively assessed MR imaging MS comparison study pairs acquired between 2009 and 2011 (161 comparison study pairs met the study inclusion criteria). Lesion detection and reading times were recorded. We tested inter- and intraobserver agreement and

SUBMITTER: van Heerden J 

PROVIDER: S-EPMC7964704 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature