Toward patient-tailored perfusion thresholds for prediction of stroke outcome.

ABSTRACT:

Background and purpose

Multiple patient-specific clinical and radiologic parameters impact traditional perfusion thresholds used to classify/determine tissue outcome. We sought to determine whether modified baseline perfusion thresholds calculated by integrating baseline perfusion and clinical factors better predict tissue fate and clinical outcome.

Materials and methods

CTP within 4.5 hours of acute anterior circulation stroke onset and 5- to 7-day MR imaging were performed for 203 patients with stroke, divided into derivation (n = 114) and validation (n = 89) data bases. Affected regions were operationally classified as infarct and noninfarct according to baseline CTP and follow-up FLAIR imaging. Perfusion thresholds were derived for each of the infarct and noninfarct regi

SUBMITTER: Eilaghi A 

PROVIDER: S-EPMC7964729 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature