Hemorrhagic risk of recent silent cerebral infarct on prethrombolysis MR imaging in acute stroke.

ABSTRACT:

Background and purpose

EIH is a rare complication after thrombolysis in patients with acute stroke, occurring in brain regions without visible ischemic change on pretreatment imaging. RSCIs can be detected by multimodal MR imaging and might be associated with an increased risk of HT postthrombolysis, related to BBBD. We aimed to assess the incidence of RSCI on pretreatment MR imaging and the subsequent risk of HT within RSCI areas on follow-up CT performed <36 hours after rtPA administration and on additional cerebral imaging before patient discharge.

Materials and methods

Pretreatment MR imaging was retrospectively analyzed from consecutive patients with stroke who received intravenous or intra-arterial rtPA for 2 years. RSCI was defined on MR imaging as a parenchymal area

SUBMITTER: Gaillard N 

PROVIDER: S-EPMC7964816 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature