Discrimination between metastasis and glioblastoma multiforme based on morphometric analysis of MR images.

ABSTRACT:

Background and purpose

Solitary MET and GBM are difficult to distinguish by using MR imaging. Differentiation is useful before any metastatic work-up or biopsy. Our hypothesis was that MET and GBM tumors differ in morphology. Shape analysis was proposed as an indicator for discriminating these 2 types of brain pathologies. The purpose of this study was to evaluate the accuracy of this approach in the discrimination of GBMs and brain METs.

Materials and methods

The dataset consisted of 33 brain MR imaging sets of untreated patients, of which 18 patients were diagnosed as having a GBM and 15 patients, as having solitary metastatic brain tumor. The MR imaging was segmented by using the K-means algorithm. The resulting set of classes (also called "clusters") represented the vari

SUBMITTER: Blanchet L 

PROVIDER: S-EPMC7964969 | biostudies-literature | 2011 Jan

REPOSITORIES: biostudies-literature