Cost-effectiveness of CT perfusion for selecting patients for intravenous thrombolysis: a US hospital perspective.

ABSTRACT:

Background and purpose

Improved selection of patients with stroke for IV tPA treatment may enhance clinical outcomes. Given the limited availability of MR imaging in hospitals, we examined the cost-effectiveness of adding CTP to the usual CT-based methods for selecting patients on the basis of the presence and extent of penumbra.

Materials and methods

A decision-analytic model estimated the costs and outcomes associated with penumbra-based CTP selection in a patient population similar to that enrolled in the IV tPA clinical trials. Model inputs were obtained from published literature, clinical trial data, standard US costing sources, and expert opinion. Cost per life-year saved and cost per QALY gained were estimated from a hospital perspective.

Results

Addition of pe

SUBMITTER: Jackson D 

PROVIDER: S-EPMC7965001 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature