Analysis of the influence of 4D MR angiography temporal resolution on time-to-peak estimation error for different cerebral vessel structures.

ABSTRACT:

Background and purpose

Time-resolved MRA imaging is a promising technique for blood flow evaluation in case of cerebrovascular malformations. Unfortunately, 4D MRA imaging is a trade-off between spatial and temporal resolution. The aim of this study was to investigate the influence of temporal resolution on the error associated with TTP estimation from indicator dilution curves derived from different vascular structures.

Materials and methods

Monte Carlo simulation was performed to compute indicator dilution curves with known criterion standard TTP at temporal resolutions between 0.1 and 5 seconds. TTPs were estimated directly and by using 4 hemodynamic models for each curve and were compared with criterion standard TTP. Furthermore, clinical evaluation was performed by usin

SUBMITTER: Forkert ND 

PROVIDER: S-EPMC7965574 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature