Right Ventricular Dysfunction in Early Sepsis and Septic Shock.

ABSTRACT:

Background

Sepsis is a frequently lethal state, commonly associated with left ventricular (LV) dysfunction. Right ventricular (RV) dysfunction in sepsis is less well understood.

Research question

In septic patients, how common is RV dysfunction, and is it associated with worse outcomes?

Study design and methods

We measured echocardiographic parameters on critically ill patients with severe sepsis or septic shock within the first 24 hours of ICU admission. We defined RV dysfunction as fractional area change (FAC) less than 35% or tricuspid annulus systolic plane excursion (TAPSE) less than 1.6 cm. We defined LV systolic dysfunction as ejection fraction (EF) less than 45% or longitudinal strain greater than -19%. Using logistic regression, we assessed the relationship b

SUBMITTER: Lanspa MJ 

PROVIDER: S-EPMC7965651 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature