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Arterial spin-labeled perfusion of pediatric brain tumors.


ABSTRACT:

Background and purpose

Pediatric brain tumors have diverse pathologic features, which poses diagnostic challenges. Although perfusion evaluation of adult tumors is well established, hemodynamic properties are not well characterized in children. Our goal was to apply arterial spin-labeling perfusion for various pathologic types of pediatric brain tumors and evaluate the role of arterial spin-labeling in the prediction of tumor grade.

Materials and methods

Arterial spin-labeling perfusion of 54 children (mean age, 7.5 years; 33 boys and 21 girls) with treatment-naive brain tumors was retrospectively evaluated. The 3D pseudocontinuous spin-echo arterial spin-labeling technique was acquired at 3T MR imaging. Maximal relative tumor blood flow was obtained by use of the ROI method

SUBMITTER: Yeom KW 

PROVIDER: S-EPMC7965744 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature