A lack of consistent brain alterations in insomnia disorder: An activation likelihood estimation meta-analysis.

ABSTRACT: Insomnia disorder is a prevalent sleep disorder, which affects about 10% of general population. However, its neural mechanisms are poorly understood. Recently, several structural and functional neuroimaging studies have been conducted in patients with insomnia disorder, but these studies have yielded diverse findings. Here, we aimed to identify consistent patterns of abnormal brain alterations in insomnia disorder by performing a quantitative coordinate-based meta-analysis. Following the preferred reporting for systematic reviews and meta-analyses statement, we searched PubMed database and used reference tracking and finally retrieved 19 eligible studies (six task-based functional magnetic resonance imaging, eight resting-state functional magnetic resonance imaging, three voxel-based morph

SUBMITTER: Tahmasian M 

PROVIDER: S-EPMC7965842 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature