Perianeurysmal brain inflammation after flow-diversion treatment.

ABSTRACT:

Background and purpose

Flow-diverter stents are an alternative treatment for challenging and recurrent aneurysms. Thrombosis of the sac is thought to induce perianeurysmal brain inflammation, but such phenomena have never been studied in flow-diverter devices. We developed imaging data to explain the clinical exacerbation of symptoms after flow-diversion treatment.

Materials and methods

Seventeen patients with unruptured aneurysms were treated by using a flow-diverter device. Clinical symptoms and angiographic and MR imaging features were recorded before and after treatment, during both the acute and chronic phases, to look for inflammatory reaction.

Results

Seven of the 17 patients (41%) showed a delayed clinical aggravation of symptoms posttreatment consisting of a

SUBMITTER: Berge J 

PROVIDER: S-EPMC7966003 | biostudies-literature | 2011 Nov-Dec

REPOSITORIES: biostudies-literature