Time-shift homotopic connectivity in mesial temporal lobe epilepsy.

ABSTRACT:

Background and purpose

Voxel-mirrored intrinsic functional connectivity allows the depiction of interhemispheric homotopic connections in the human brain, whereas time-shift intrinsic functional connectivity allows the detection of the extent of brain injury by measuring hemodynamic properties. We combined time-shift voxel-mirrored homotopic connectivity analyses to investigate the alterations in homotopic connectivity in mesial temporal lobe epilepsy and assessed the value of applying this approach to epilepsy lateralization and the prediction of surgical outcomes in mesial temporal lobe epilepsy.

Materials and methods

Resting-state functional MR imaging data were acquired from patients with unilateral mesial temporal lobe epilepsy (n=62) (31 left- and 31 right-side) and he

SUBMITTER: Xu Q 

PROVIDER: S-EPMC7966270 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature