Computational hemodynamics analysis of intracranial aneurysms treated with flow diverters: correlation with clinical outcomes.

ABSTRACT:

Background and purpose

Recent studies have shown promising results regarding intracranial aneurysms treated with flow diverters. However, these have had adverse effects, including delayed aneurysm occlusion, posttreatment symptoms, and rupture. The hemodynamic profiles of aneurysms treated with flow diverters were analyzed to determine the ones associated with successful and failed treatments.

Materials and methods

Patient-specific computational fluid dynamics were used to simulate hemodynamic profiles, including the presence of jet flow, energy loss, volume flow, and wall shear stress in 4 successful occlusions of aneurysms and 4 failed cases after flow-diverter deployment. In these 4 failed cases, hemodynamic profiles were examined again after a hypothetic second intervent

SUBMITTER: Chong W 

PROVIDER: S-EPMC7966473 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature