Brain MR findings in patients with systemic lupus erythematosus with and without antiphospholipid antibody syndrome.

ABSTRACT:

Background and purpose

Antiphospholipid syndrome may affect the incidence and pathogenesis of cerebrovascular diseases in patients with systemic lupus erythematosus. We compared the spectrum of MR findings in patients with systemic lupus erythematosus with and without antiphospholipid syndrome.

Materials and methods

We identified 256 patients with systemic lupus erythematosus (45 with, 211 without antiphospholipid syndrome) who underwent MR studies; in 145 (57%), we detected abnormalities. These were categorized as large territorial, lacunar, localized cortical, and borderzone infarctions and as microembolisms, basal ganglia lesions, callosal lesions, hemorrhages, and white matter hyperintensity on T2-weighted and/or FLAIR images, and as stenotic arterial lesions on MR angio

SUBMITTER: Kaichi Y 

PROVIDER: S-EPMC7966497 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature