Stability in brain glucose metabolism following brown adipose tissue inactivation in chinese adults.

ABSTRACT:

Background and purpose

The thermogenesis of BAT is believed to be controlled through some pathways initiated in the brain, though the changes in brain activity among different states of BAT-positive subjects are still unclear. We hypothesized that some significant differences of regional cerebral metabolism between various groups were related to the BAT activities regardless of temperature changes.

Materials and methods

Relative regional cerebral glucose metabolism was compared between 15 healthy subjects with activated BAT and 30 healthy controls without activated BAT by using a brain FDG-PET scan. A follow-up PET scan was performed to assess metabolic changes of the brain when BAT activity was eliminated by heat exposure.

Results

Compared with controls, BAT-positive

SUBMITTER: Miao Q 

PROVIDER: S-EPMC7966559 | biostudies-literature | 2012 Sep

REPOSITORIES: biostudies-literature