Surgery for IDH1/2 wild-type glioma invading the corpus callosum.

ABSTRACT:

Background

Glioblastoma of the corpus callosum (ccGBM) are rare tumors, with a dismal prognosis marked by a rapid clinical deterioration. For a long time, surgical treatment was not considered beneficial for most patients with such tumors. Recent studies claimed an improved survival for patients undergoing extensive resection, albeit without integration of the molecular profile of the lesions. The purpose of this study was to investigate the effect of biopsy and surgical resection on oncological and functional outcomes in patients with IDH wild-type ccGBM.

Methods

We performed a retrospective analysis of our institution's database of patients having been treated for high-grade glioma between 2005 and 2017. Inclusion criteria were defined as follows: patients older than 18 ye

SUBMITTER: Franco P 

PROVIDER: S-EPMC7966629 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature