Topical bromfenac reduces multiple inflammatory cytokines in the aqueous humour of pseudophakic patients.

ABSTRACT: Intraocular surgery is associated with increased ocular inflammation. If maintained for a prolonged period after surgery, this inflammation can cause various complications, including subconjunctival fibrosis and bleb scarring. This clinical trial was a prospective, randomised, single-blind, interventional study comparing the efficacy and safety of 0.1% bromfenac sodium ophthalmic solution and 0.02% fluorometholone ophthalmic suspension in the inhibition of multiple inflammatory cytokines in the aqueous humour of 26 patients with pseudophakic eyes who had undergone phacoemulsification and intraocular lens implantation. The patients were randomly assigned to one of the trial drugs, and aqueous humour samples were collected before and after drug administration. Platelet-derived growth factor-

SUBMITTER: Matsumura T 

PROVIDER: S-EPMC7966778 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature