Synergistic Ice Inhibition Effect Enhances Rapid Freezing Cryopreservation with Low Concentration of Cryoprotectants.

ABSTRACT: Despite recent advances in controlling ice formation and growth, it remains a challenge to design anti-icing materials in various fields from atmospheric to biological cryopreservation. Herein, tungsten diselenide (WSe₂)-polyvinyl pyrrolidone (PVP) nanoparticles (NPs) are synthesized through one-step solvothermal route. The WSe₂-PVP NPs show synergetic ice regulation ability both in the freezing and thawing processes. Molecularly speaking, PVP containing amides group can form hydrogen bonds with water molecules. At a macro level, the WSe₂-PVP NPs show adsorption-inhibition and photothermal conversation effects to synergistically restrict ice growth. Meanwhile, WSe₂-PVP NPs are for the first time used for the cryopreservation of human umbilical ve

SUBMITTER: Chang T 

PROVIDER: S-EPMC7967066 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature