COVID-19 highlights the model dilemma in biomedical research.

ABSTRACT: Scientists worldwide struggle to identify suitable animal models to study SARS-CoV-2 infections. Interspecies-related differences, such as host specificity, divergent immune responses, or the unavailability of species-specific reagents hamper the research. Human-based models, such as micro-engineered multi-organs-on-chip, may hold the solution.

SUBMITTER: Adhikary PP 

PROVIDER: S-EPMC7967778 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature