Day 5 versus Day 6 blastocyst transfers: a systematic review and meta-analysis of clinical outcomes.

ABSTRACT:

Study question

Is there a difference in clinical pregnancy and live birth rates (LBRs) between blastocysts developing on Day 5 (D5) and blastocysts developing on Day 6 (D6) following fresh and frozen transfers?

Summary answer

D5 blastocyst transfers (BTs) present higher clinical pregnancy and LBRs than D6 in both fresh and frozen transfers.

What is known already

BT is increasingly popular in assisted reproductive technology (ART) centers today. To our knowledge, no meta-analysis has focused on clinical outcomes in both fresh and frozen BT. Concerning frozen blastocysts, one meta-analysis in 2010 found no significant difference in pregnancy outcomes between D5 and D6 BT. Since then, ART practices have evolved particularly with the wide use of vitrification, and more ar

SUBMITTER: Bourdon M 

PROVIDER: S-EPMC7967799 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature