Neck circumference as an independent predictor for NAFLD among postmenopausal women with normal body mass index.

ABSTRACT:

Background

Neck circumference, a proxy for upper-body subcutaneous fat, is a unique and pathogenic fat depot that confers additional metabolic risk. The purpose of present study was to determine whether neck circumference associates with nonalcoholic fatty liver disease (NAFLD) in postmenopausal women with normal body mass index.

Methods

A cross-sectional survey (n = 2492) and a 3.1-year follow-up investigation (n = 1354) were conducted among Chinese postmenopausal women with normal BMI (18.5 to < 25 kg/m²). Neck circumference was measured horizontally at the lower margin of the laryngeal prominence.

Results

In the cross-sectional analysis, large neck circumference was associated with the presence of NAFLD (odds ratio 2.28; 95% CI 1.74-2.98; highest tertile

SUBMITTER: Shi J 

PROVIDER: S-EPMC7967966 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature