Signal, bias, and the role of transcriptome assembly quality in phylogenomic inference.

ABSTRACT:

Background

Phylogenomic approaches have great power to reconstruct evolutionary histories, however they rely on multi-step processes in which each stage has the potential to affect the accuracy of the final result. Many studies have empirically tested and established methodology for resolving robust phylogenies, including selecting appropriate evolutionary models, identifying orthologs, or isolating partitions with strong phylogenetic signal. However, few have investigated errors that may be initiated at earlier stages of the analysis. Biases introduced during the generation of the phylogenomic dataset itself could produce downstream effects on analyses of evolutionary history. Transcriptomes are widely used in phylogenomics studies, though there is little understanding of how a po

SUBMITTER: Spillane JL 

PROVIDER: S-EPMC7968300 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature