Regression patterns of uveal melanoma after iodine-125 plaque brachytherapy.

ABSTRACT:

Background

Tumor regression of uveal melanomas (UMs) after radiotherapy has been reported as a valuable prognostic factor for metastasis and metastatic death. But its effect on prognosis is questionable. The purpose of this study was to summarize the regression features of uveal melanoma after iodine-125 plaque brachytherapy and the relationship with prognosis.

Methods

Adult uveal melanoma patients who only received iodine-125 plaque brachytherapy between December 2009 and March 2018 at the Beijing Tongren Hospital, Capital Medical University were enrolled in this study. The regression rate was calculated as the percent change in tumor height, and each eye was classified for four main regression patterns: Decrease (D), Stable (S), Others (O), and Increase (I), according to t

SUBMITTER: Fang R 

PROVIDER: S-EPMC7968312 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature