Non-resuscitation fluid in excess of hydration requirements is associated with higher mortality in critically ill children.

ABSTRACT:

Background

Large volumes of non-resuscitation fluids are often administered to critically ill children. We hypothesize that excess maintenance fluid is a significant contributor to non-resuscitation fluid and that non-resuscitation fluid administered beyond hydration requirements is associated with worse clinical outcomes in critically ill children.

Methods

We evaluated all patients admitted to two large urban pediatric intensive care units (PICU) between January 2010-August 2016 and January 2010-August 2018, respectively, who survived and remained in the hospital for at least 3 days following PICU admission. The primary outcome was in-hospital mortality. Association of excess fluid with outcomes was adjusted for confounders (age, Pediatric Risk of Mortality III score, study

SUBMITTER: Barhight MF 

PROVIDER: S-EPMC7968408 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature