Frailty as a predictor of mortality among patients with COVID-19: a systematic review and meta-analysis.

ABSTRACT:

Background

A large number of studies have explored the association between frailty and mortality among COVID-19 patients, with inconsistent results. The aim of this meta-analysis was to synthesize the evidence on this issue.

Methods

Three databases, PubMed, Embase, and Cochrane Library, from inception to 20th January 2021 were searched for relevant literature. The Newcastle-Ottawa Scale (NOS) was used to assess quality bias, and STATA was employed to pool the effect size by a random effects model. Additionally, potential publication bias and sensitivity analyses were performed.

Results

Fifteen studies were included, with a total of 23,944 COVID-19 patients, for quantitative analysis. Overall, the pooled prevalence of frailty was 51% (95% CI: 44-59%). Patients with fra

SUBMITTER: Zhang XM 

PROVIDER: S-EPMC7968577 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature