HIV viral load and pregnancy loss: results from a population-based cohort study in rural KwaZulu-Natal, South Africa.

ABSTRACT:

Objective

With ever-expanding antiretroviral therapy (ART) access among pregnant women in sub-Saharan Africa, it is more than ever important to address the gap in knowledge around ART effectiveness, as measured by HIV viral load, and pregnancy loss.

Design

A population-based cohort study.

Methods

The study sample consisted of 3431 pregnancies from 2835 women living with HIV aged 16-35 years old. All women participated in a population-based cohort conducted between 2004 and 2018 in rural KwaZulu-Natal, South Africa. Viral load data were collected at prior surveys and an HIV care registry. The closest available viral load to the date that each pregnancy ended was used and classified as either a pre- or postconception viral load. Logistic regression was used to investiga

SUBMITTER: Moodley Y 

PROVIDER: S-EPMC7969410 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature