Non-targeted tandem mass spectrometry enables the visualization of organic matter chemotype shifts in coastal seawater.

ABSTRACT: Urbanization along coastlines alters marine ecosystems including contributing molecules of anthropogenic origin to the coastal dissolved organic matter (DOM) pool. A broad assessment of the nature and extent of anthropogenic impacts on coastal ecosystems is urgently needed to inform regulatory guidelines and ecosystem management. Recently, non-targeted tandem mass spectrometry approaches are gaining momentum for the analysis of global organic matter composition (chemotypes) including a wide array of natural and anthropogenic compounds. In line with these efforts, we developed a non-targeted liquid chromatography tandem mass spectrometry (LC-MS/MS) workflow that utilizes advanced data analysis approaches such as feature-based molecular networking and repository-scale spectrum searches. This

SUBMITTER: Petras D 

PROVIDER: S-EPMC7969459 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature