Dynamic Changes in Microbial Composition During Necrotizing Soft-Tissue Infections in ICU Patients.

ABSTRACT: Introduction: Recent studies described the threat of emerging multidrug-resistant (MDR) bacteria in intensive care unit (ICU) patients, but few data are available for necrotizing skin and soft tissue infections (NSTI). In a cohort of ICU patients admitted for NSTI, we describe the dynamic changes of microbial population during repeated surgeries. Materials and Methods: This retrospective study compiled consecutive cases admitted for the management of severe NSTI. Clinical characteristics, NSTI features, morbidity and mortality data were collected. The microbiological characteristics of surgical samples obtained during initial surgery were compared with those obtained during the first reoperation, including persistence of initial pathogens and/or emergence of microorganisms. R

SUBMITTER: Thy M 

PROVIDER: S-EPMC7969649 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature