Omitting TMS component from paired associative stimulation with high-frequency PNS: A case series of tetraplegic patients.

ABSTRACT:

Objectives

Earlier studies have shown how chronic spinal cord injury (SCI) patients have benefitted from paired associative stimulation (PAS), consisting of high-frequency peripheral nerve stimulation (PNS) and high-intensity transcranial magnetic stimulation (TMS). Since high-frequency PNS is poorly characterized, its therapeutic effect without TMS should be evaluated. We tested the effect of PNS combined with motor imagery in chronic SCI patients using the same parameters of PNS as in earlier PAS-based studies that also used TMS.

Methods

Five patients with chronic incomplete SCI and tetraplegia received a 6-week treatment of PNS combined with motor imagery to the weaker upper limb. Patients were evaluated with Manual Muscle Testing (MMT), hand function tests (Box and block

SUBMITTER: Pohjonen M 

PROVIDER: S-EPMC7970010 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature