Stress Myocardial Perfusion PET Provides Incremental Risk Prediction in Patients with and Patients without Diabetes.

ABSTRACT:

Purpose

To evaluate the prognostic value of myocardial perfusion PET in patients with and patients without diabetes mellitus.

Materials and methods

The authors performed a retrospective analysis of prospectively acquired data from a multicenter registry cohort of 7061 patients, including 1966 with diabetes mellitus, who underwent clinically indicated rest-stress rubidium 82 (⁸²Rb) myocardial perfusion PET. The mean patient age (±standard deviation) was 63.3 years ± 13. Of the 7061 patients, 3348 were women (47.4%), 2296 (32.5%) had known coronary artery disease, and 1895 (26.8%) had previously undergone revascularization. The primary end point was cardiac death (n = 169) assessed at a mean of 2.5 years ± 1.5. The authors used Cox proportional hazards models

SUBMITTER: Skali H 

PROVIDER: S-EPMC7970097 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature