STATegra: Multi-Omics Data Integration - A Conceptual Scheme With a Bioinformatics Pipeline.

ABSTRACT: Technologies for profiling samples using different omics platforms have been at the forefront since the human genome project. Large-scale multi-omics data hold the promise of deciphering different regulatory layers. Yet, while there is a myriad of bioinformatics tools, each multi-omics analysis appears to start from scratch with an arbitrary decision over which tools to use and how to combine them. Therefore, it is an unmet need to conceptualize how to integrate such data and implement and validate pipelines in different cases. We have designed a conceptual framework (STATegra), aiming it to be as generic as possible for multi-omics analysis, combining available multi-omic anlaysis tools (machine learning component analysis, non-parametric data combination, and a multi-omics exploratory an

SUBMITTER: Planell N 

PROVIDER: S-EPMC7970106 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature