Cognitive profiles in obstructive sleep apnea: a cluster analysis in sleep clinic and community samples.

ABSTRACT:

Study objectives

Although cognitive dysfunction is a recognized consequence of untreated obstructive sleep apnea (OSA), the deficit pattern is heterogeneous. Understanding this heterogeneity may identify those at risk of cognitive deficits and guide intervention strategies. To facilitate understanding, we examined whether distinct profiles of neuropsychological performance were present in OSA and, if so, how they are related to other OSA features.

Methods

We studied sleep clinic (n = 121) and community (n = 398) samples with moderate-severe OSA (apnea-hypopnea index ≥ 15 events/h). Attention and memory were assessed using the Cognitive Drug Research system. Sleep was assessed using polysomnography in the clinic sample and dual channel (flow, oximetry) portable monitoring in

SUBMITTER: Olaithe M 

PROVIDER: S-EPMC7970596 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature