Slow-oscillation activity is reduced and high frequency activity is elevated in older adults with insomnia.

ABSTRACT:

Study objectives

High-frequency electroencephalographic activity (> 16 Hz activity) is often elevated during nonrapid eye movement sleep among individuals with insomnia, in line with the hyperarousal theory of insomnia. Evidence regarding sleep depth marked by slow-wave activity (< 4 Hz) is more mixed. Distinguishing subcomponents of slow-wave activity (slow-oscillation [< 1 Hz] or delta activity [1-4 Hz)]) may be critical in understanding these discrepancies, given that these oscillations have different neural generators and are functionally distinct. Here we tested the effects of insomnia diagnosis and insomnia treatment on nonrapid eye movement electroencephalography in older adults, distinguishing slow-oscillation and delta power.

Methods

In 93 older adults with insomnia

SUBMITTER: Hogan SE 

PROVIDER: S-EPMC7970605 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature