Three-dimensional evaluation of the effects of injectable platelet rich fibrin (i-PRF) on alveolar bone and root length during orthodontic treatment: a randomized split mouth trial.

ABSTRACT:

Background

The role of injectable platelet rich fibrin (i-PRF) in orthodontic treatment has not been investigated with focus on its effect on dental and bony periodontal elements.

Objective

To evaluate the efficacy of i-PRF in bone preservation and prevention of root resorption.

Methods

A randomized split-mouth controlled trial included 21 patients aged 16-28 years (20.85 ± 3.85), who were treated for Class II malocclusion with the extraction of the maxillary first premolars. Right and left sides were randomly allocated to either experimental treated with i-PRF or control sides. After the leveling and alignment phase, the canines were retracted with 150gm forces. The i-PRF was prepared from the blood of each patient following a precise protocol, then injected immediat

SUBMITTER: Zeitounlouian TS 

PROVIDER: S-EPMC7971145 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature