Rate-Dependent and Relaxation Properties of Porcine Aortic Heart Valve Biomaterials.

ABSTRACT:

Objective

This work evaluates the rate-dependent and relaxation properties of native porcine heart valves, glutaraldehyde fixed porcine pericardium, and decellularized sterilized porcine pericardium.

Methods

Biaxial tension testing was performed at strain-rates of 0.001 s^-1, 0.01 s^-1, 0.1 s^-1, and 1 s^-1. Finally, relaxation testing for 300 s was performed on all heart valve biomaterials.

Results

No notable rate-dependent response was observed for any of the three biomaterials with few significant differences between any strain-rates. For relaxation testing, native tissues showed the most pronounced drop in stress and glutaraldehyde the lowest drop in stress although no tissues showed anisotropy in the relaxation.

Conclusi

SUBMITTER: Noble C 

PROVIDER: S-EPMC7971416 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature